A goalless draw at home to Benfica final month left Barca with their future in their personal palms, however with a far trickier very last game away to Group E winners Bayern Munich.
Spanish champions Atletico Madrid have their paintings cut to secure one of the 5 unclaimed ultimate-16 tickets after three defeats at the spin, while all 4 groups stay in the hunt in an unpredictable Group G.
AFP Sport looks at what is at stake going into the final spherical of Champions League institution video games:
Ballon d'Or backlash from Bayern?
Barca find themselves on the ropes in advance of Wednesday's journey to Germany, but it may were a ways worse had been it not for Benfica forward Haris Seferovic's obtrusive leave out in stoppage time at Camp Nou.
Bayern are certainly one of three groups with a super file on this season's competition, and Robert Lewandowski's perceived Ballon d'Or snub may also deliver the megastar striker greater incentive to show a point.
Xavi suffered his first defeat as Barca instruct on Saturday in opposition to Real Betis. He rested key players a good way to the game in Munich, where victory might assure Barca go through as runners-up in Group E, extending their 20-12 months run of attaining the knockout phase.
A younger Xavi was setting up himself as a mainstay of the midfield when Barca exited inside the first group stage of the 2000-01 opposition.
Failure to steady most factors might open the door for Benfica to pip them to second region, with the Portuguese needing to conquer Dynamo Kiev in Lisbon.
Three-horse race and 4-way showdown