"It was a honestly horrific day from us, we awoke too late. St Pauli did well, however we are out," Dortmund captain Marco Reus stated after the match.
The hosts took an early lead thru Togo striker Etienne Amenyido, then Dortmund midfielder Axel Witsel scored an own goal.
Star striker Erling Haaland gave Dortmund hope with the aid of converting a 2nd-half of penalty, but the visitors did not pressure an equaliser.
The end result way neither Dortmund nor Bayern Munich, who suffered a humiliating 5-0 defeat at Borussia Moenchengladbach inside the previous round in October, may be in the area-very last draw for the primary time given that 2006/07.
St Pauli, currently pinnacle of the second one Bundesliga table, were ahead after four minutes while Amenyido got in among Dortmund captain Marco Reus and Manuel Akanji to transform a pass.
Amenyido's shocked expression throughout his celebrations showed he ought to slightly consider his good fortune while there have been ashen faces within the Dortmund defence.
The away facet's problems were compounded when they were 2-0 down at half-time after Witsel grew to become the ball into his personal net simply before the damage whilst seeking to block a pass to Amenyido.
Dortmund grabbed a lifeline whilst Mats Hummels' bypass clipped the outstretched arm of St Pauli defender Jakov Medic in the field and Haaland transformed the resulting penalty simply before the hour mark.
Dortmund pushed for an equaliser, but Reus and Donyell Malen both squandering chances.
