Klopp's side visit City on Sunday in a important conflict in the Premier League title race.
Second positioned Liverpool are one factor at the back of leaders City with eight video games left for each groups.
A win for Liverpool might put them in pole position to boost the Premier League trophy for a 2d time in three seasons.
But a Liverpool defeat or even a draw would leave reigning champions City as the favourites to hold the identify.
That could be a bitter blow for Liverpool, given their splendid form of late, but it would now not be the primary time they were not able to seize City notwithstanding playing at the height of their powers.
In 2018-19, City pipped Liverpool to the title via a factor no matter the Reds' report factors haul for the runners-up.
Klopp knows City are by using a long way the hardest opponent his crew will face as they chase an exceptional quadruple.
"There is no sport in international football you may compare to play against City because they may be true in quite a whole lot all areas. There are not any actual weaknesses," Klopp advised journalists on Friday.
"You have to reveal the respect they deserve, particularly against City as they're quite precise with the ball.
"We understand it is hard. What's modified this closing four years is all people else thinks it is tough once they face us, and that's actually suitable.