Martin Odegaard neglected Thursday's goalless League Cup semi-very last first-leg draw at Liverpool because of Covid-19, with Emile Smith Rowe and Takehiro Tomiyasu dominated out thru harm.
Cedric Soares and Bukayo Saka suffered accidents at Anfield in a fit where Granit Xhaka was despatched off.
Arsenal were already without Thomas Partey, Mohamed Elneny, Nicolas Pepe and Pierre-Emerick Aubameyang due to their AFCON commitments.
"We can verify we have made an application to the Premier League for the postponement of Sunday's north London derby in opposition to Tottenham Hotspur," stated an Arsenal assertion.
"We have reluctantly taken this step however we've got many players currently unavailable throughout our squad as a result of Covid, accidents and gamers away with their nations at AFCON."
Arsenal supervisor Mikel Arteta, speakme in advance on Friday, become uncertain about whether the healthy might go ahead.
"I don't know, it is difficult to mention that with overall honesty without assessing our gamers," he stated when requested if he would like the game to be called off.
"What is today not possible, day after today is likely to appear. It's long past the opposite manner for us when we had been equipped to play a match and it became cancelled two times because the other group had troubles so it could go each methods. But our intention is always to play."
Fifth-positioned Arsenal are two points ahead of Tottenham, however Spurs have two games in hand.