Elsewhere, Liverpool will are searching for to make it seven league wins in seven towards high-flying West Ham, considered one of handiest aspects to beat the Reds this season.
Arsenal should take gain of visits to the pinnacle for the Hammers and United by means of moving into fourth with video games in hand to come back when they journey to Watford.
AFP Sport takes a have a look at a number of the key speakme factors in advance of the weekend motion.
Can City end United Etihad jinx?
Even even though they're now no doubt the pinnacle dogs in Manchester, City have had actual problems beating United on their own turf in latest years.
The Premier League champions have received simply one in every of their past seven domestic games in all competitions in opposition to United -- in sharp comparison to their spectacular report at Old Trafford.
Both teams want the three factors on Sunday, with leaders City looking for to hold Jurgen Klopp's charging Liverpool at arm's period and United's pinnacle-4 hopes looking shaky.
The fourth-positioned Reds are simply points in advance of West Ham and Arsenal as they seek to steady Champions League qualification for next season, even as the Gunners have 3 games in hand.
City, who have a tendency to dominate ownership, have been caught out in latest years by using United's pace at the damage and Pep Guardiola could be wary of the risk posed by way of players such as Jadon Sancho and Marcus Rashford.
United have misplaced simply one league sport in view that period in-between supervisor Ralf Rangnick took price in December but that is through some distance his hardest assignment but.
